Determining Genetic Risk

Case 2 - Cystic Fibrosis

Family history:

Your patient, Leah, a 27 year-old Caucasian woman, reports that her sister and brother died from complications associated with Cystic Fibrosis(CF). Cystic Fibrosis is a genetic condition which occurs in 1/2500 Caucasian births. Leah does not believe that anyone else in her extended family was affected with the disease. Her husband, Dave, does not have a family history of CF. He is also Caucasian. Leah is 16 weeks pregnant.